Publications

2023

Islam, S.T., Cheng, C., Parreno, J., Fowler, V.M., 2023. Nonmuscle Myosin IIA Regulates the Precise Alignment of Hexagonal Eye Lens Epithelial Cells During Fiber Cell Formation and Differentiation. Invest Ophthalmol Vis Sci 64, 20. https://doi.org/10.1167/iovs.64.4.20

2022

Ghosh, A., Coffin, M., West, R., Fowler, V.M., 2022. Erythroid differentiation in mouse erythroleukemia cells depends on Tmod3-mediated regulation of actin filament assembly into the erythroblast membrane skeleton. FASEB J 36, e22220. https://doi.org/10.1096/fj.202101011R
Nowak, R.B., Alimohamadi, H., Pestonjamasp, K., Rangamani, P., Fowler, V.M., 2022. Nanoscale dynamics of actin filaments in the red blood cell membrane skeleton. Mol Biol Cell 33, ar28. https://doi.org/10.1091/mbc.E21-03-0107
Trevorrow, P., Fowler, V.M., 2022. An interview with Velia M. Fowler, Department of Biological Sciences, University of Delaware, DE, USA. Cytoskeleton (Hoboken) 79, 119–121. https://doi.org/10.1002/cm.21730
Zhou, R., Han, B., Nowak, R., Lu, Y., Heller, E., Xia, C., Chishti, A.H., Fowler, V.M., Zhuang, X., 2022. Proteomic and functional analyses of the periodic membrane skeleton in neurons. Nat Commun 13, 3196. https://doi.org/10.1038/s41467-022-30720-x

2021

Ghosh, A., Fowler, V.M., 2021. Tropomodulins. Curr Biol 31, R501–R503. https://doi.org/10.1016/j.cub.2021.01.055

2020

Alimohamadi, H., Smith, A.S., Nowak, R.B., Fowler, V.M., Rangamani, P., 2020. Non-uniform distribution of myosin-mediated forces governs red blood cell membrane curvature through tension modulation. PLoS Comput Biol 16, e1007890. https://doi.org/10.1371/journal.pcbi.1007890
Barnum CE, Al Saai S, Patel SD, et al. The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology. Human Molecular Genetics. 2020;29(12):2076-2097. doi:10.1093/hmg/ddaa096
Pal, K., Nowak, R., Billington, N., Liu, R., Ghosh, A., Sellers, J.R., Fowler, V.M., 2020. Megakaryocyte migration defects due to nonmuscle myosin IIA mutations underlie thrombocytopenia in MYH9-related disease. Blood 135, 1887–1898. https://doi.org/10.1182/blood.2019003064
Parreno, J., Amadeo, M.B., Kwon, E.H., Fowler, V.M., 2020. Tropomyosin 3.1 Association With Actin Stress Fibers is Required for Lens Epithelial to Mesenchymal Transition. Invest Ophthalmol Vis Sci 61, 2. https://doi.org/10.1167/iovs.61.6.2

2019

Cheng, C., Parreno, J., Nowak, R.B., Biswas, S.K., Wang, K., Hoshino, M., Uesugi, K., Yagi, N., Moncaster, J.A., Lo, W.-K., Pierscionek, B., Fowler, V.M., 2019. Age-related changes in eye lens biomechanics, morphology, refractive index and transparency. Aging (Albany NY) 11, 12497–12531. https://doi.org/10.18632/aging.102584
Smith, A.S., Pal, K., Nowak, R.B., Demenko, A., Zaninetti, C., Da Costa, L., Favier, R., Pecci, A., Fowler, V.M., 2019. MYH9-related disease mutations cause abnormal red blood cell morphology through increased myosin-actin binding at the membrane. Am J Hematol 94, 667–677. https://doi.org/10.1002/ajh.25472
Zhao, Y., Wilmarth, P.A., Cheng, C., Limi, S., Fowler, V.M., Zheng, D., David, L.L., Cvekl, A., 2019. Proteome-transcriptome analysis and proteome remodeling in mouse lens epithelium and fibers. Exp Eye Res 179, 32–46. https://doi.org/10.1016/j.exer.2018.10.011

2018

Cheng, C., Nowak, R.B., Amadeo, M.B., Biswas, S.K., Lo, W.-K., Fowler, V.M., 2018. Tropomyosin 3.5 protects the F-actin networks required for tissue biomechanical properties. J Cell Sci 131, jcs222042. https://doi.org/10.1242/jcs.222042
Omotade, O.F., Rui, Y., Lei, W., Yu, K., Hartzell, H.C., Fowler, V.M., Zheng, J.Q., 2018. Tropomodulin Isoform-Specific Regulation of Dendrite Development and Synapse Formation. J. Neurosci. 38, 10271–10285. https://doi.org/10.1523/JNEUROSCI.3325-17.2018
Parreno, J., Cheng, C., Nowak, R.B., Fowler, V.M., 2018. The effects of mechanical strain on mouse eye lens capsule and cellular microstructure. MBoC 29, 1963–1974. https://doi.org/10.1091/mbc.E18-01-0035
Parreno, J., Fowler, V.M., 2018. Multifunctional roles of tropomodulin-3 in regulating actin dynamics. Biophys Rev 10, 1605–1615. https://doi.org/10.1007/s12551-018-0481-9
Smith, A.S., Nowak, R.B., Fowler, V.M., 2018a. High-Resolution Fluorescence Microscope Imaging of Erythroblast Structure, in: Lloyd, J.A. (Ed.), Erythropoiesis, Methods in Molecular Biology. Springer New York, New York, NY, pp. 205–228. https://doi.org/10.1007/978-1-4939-7428-3_12
Smith, A.S., Nowak, R.B., Zhou, S., Giannetto, M., Gokhin, D.S., Papoin, J., Ghiran, I.C., Blanc, L., Wan, J., Fowler, V.M., 2018b. Myosin IIA interacts with the spectrin-actin membrane skeleton to control red blood cell membrane curvature and deformability. Proc. Natl. Acad. Sci. U.S.A. 115. https://doi.org/10.1073/pnas.1718285115